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In this review, we summarize the distinguishing clinical characteristics of vulvar melanotic macules.

In our opinion, the use and cleaning of the dermatoscope with isopropyl alcohol is sufficient to prevent nosocomial infection.

Here, we provide a brief review of dermoscopy and reflectance confocal microscopy features of melanosis of the genital and oral mucosa.

Keywords: Dermoscopy, melanosis, reflectance confocal microscopy How to cite this URL: Bombonato C, Longo C, Piana S, Moscarella E.

They are defined as a benign hyperpigmentation of the basal keratinocytes.

The number of melanocytes is normal or slightly increased, but they are not arranged in nests. Clinically, vulvar melanosis presents as a single or more commonly multiple, asymmetric macules or patches with variable shades of tan-to-black color, irregular and poorly demarcated borders, and variable size from 1 mm to 1 cm.

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Histopathologically, it is correlated with the presence of melanin in the epidermal basal cells, the lines of the network resulting from the projection of the pigmented rete ridges to the skin surface.

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