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Sometimes there are vital synergistic relationships between these various serotonin boosting substances.There are several co-factors required to make the most commonly used serotonin supplements do their job.Unfortunately, this supplement’s usefulness for depression may be more hype than substance.A review of 108 studies on 5-HTP revealed there is still no definitive evidence that it helps depression (9). An Ongoing Debate: There’s an ongoing discussion in the natural health community whether it’s better to take tryptophan or 5-HTP to increase serotonin levels.However, tryptophan supplements can increase brain serotonin even though eating foods containing tryptophan does not (5).Tryptophan supplements fell out of favor when a contaminated batch from Japan caused thousands to fall ill in the 1980s.

It is an opportunity for us to reflect on the language and ideas that represented each year.

While it’s increasing serotonin, it’s depleting other neurotransmitters like dopamine.

Within a few months, this inevitably causes a cascade of negative side effects (10). Datis Kharrazian, author of , lists these co-factors as needed for the synthesis of either tryptophan or 5-HTP to serotonin — vitamins B3, B6, and B12, folic acid, and magnesium.

So, take a stroll down memory lane to remember all of our past Word of the Year selections.

Serotonin supplements like specific amino acids, vitamins, minerals and herbs increase serotonin levels helping depression and other brain-related disorders.

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Conversely, there are times when these supplements can react adversely with medications or other serotonin supplements, and you need to know about those, too.

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